PCBP2 Enhances the Antiviral Activity of IFN-α against HCV by Stabilizing the mRNA of STAT1 and STAT...
PCBP2 Enhances the Antiviral Activity of IFN-α against HCV by Stabilizing the mRNA of STAT1 and STAT2
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Interferon-α (IFN-α) is a natural choice for the treatment of hepatitis C, but half of the chronically infected individuals do not achieve sustained clearance of hepatitis C virus (HCV) during treatment with IFN-α alone. The virus can impair IFN-α signaling and cellular factors that have an effect on the viral life cycles. We found that the protein...
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Full title
PCBP2 Enhances the Antiviral Activity of IFN-α against HCV by Stabilizing the mRNA of STAT1 and STAT2
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TN_cdi_plos_journals_1309449914
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309449914
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0025419
