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Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripot...

Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripot...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309451682

Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome

About this item

Full title

Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-10, Vol.6 (10), p.e26203

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability. In addition to cognitive deficits, FXS patients exhibit hyperactivity, attention deficits, social difficulties, anxiety, and other autistic-like behaviors. FXS is caused by an expanded CGG trinucleotide repeat in the 5' untranslated region of the Fragile X Menta...

Alternative Titles

Full title

Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1309451682

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309451682

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0026203

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