Log in to save to my catalogue

Human FasL gene is a target of β-catenin/T-cell factor pathway and complex FasL haplotypes alter pro...

Human FasL gene is a target of β-catenin/T-cell factor pathway and complex FasL haplotypes alter pro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309451911

Human FasL gene is a target of β-catenin/T-cell factor pathway and complex FasL haplotypes alter promoter functions

About this item

Full title

Human FasL gene is a target of β-catenin/T-cell factor pathway and complex FasL haplotypes alter promoter functions

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-10, Vol.6 (10), p.e26143

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

FasL expression on human immune cells and cancer cells plays important roles in immune homeostasis and in cancer development. Our previous study suggests that polymorphisms in the FasL promoter can significantly affect the gene expression in human cells. In addition to the functional FasL SNP -844C>T (rs763110), three other SNPs (SNP -756A>G or rs2...

Alternative Titles

Full title

Human FasL gene is a target of β-catenin/T-cell factor pathway and complex FasL haplotypes alter promoter functions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1309451911

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309451911

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0026143

How to access this item