Penicillin Binding Proteins as Danger Signals: Meningococcal Penicillin Binding Protein 2 Activates...
Penicillin Binding Proteins as Danger Signals: Meningococcal Penicillin Binding Protein 2 Activates Dendritic Cells through Toll-Like Receptor 4
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Author / Creator
Hill, Marcelo , Deghmane, Ala-Eddine , Segovia, Mercedes , Zarantonelli, Maria Leticia , Tilly, Gaëlle , Blancou, Philippe , Bériou, Gaëlle , Josien, Régis , Anegon, Ignacio , Hong, Eva , Ruckly, Corinne , Antignac, Aude , Ghachi, Meriem El , Boneca, Ivo Gomperts , Taha, Muhamed-Kheir and Cuturi, Maria Cristina
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Neisseria meningitidis is a human pathogen responsible for life-threatening inflammatory diseases. Meningococcal penicillin-binding proteins (PBPs) and particularly PBP2 are involved in bacterial resistance to β-lactams. Here we describe a novel function for PBP2 that activates human and mouse dendritic cells (DC) in a time and dose-dependent manne...
Alternative Titles
Full title
Penicillin Binding Proteins as Danger Signals: Meningococcal Penicillin Binding Protein 2 Activates Dendritic Cells through Toll-Like Receptor 4
Authors, Artists and Contributors
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Record Identifier
TN_cdi_plos_journals_1309830868
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1309830868
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0023995
