Essential Role of the Small GTPase Ran in Postnatal Pancreatic Islet Development
Essential Role of the Small GTPase Ran in Postnatal Pancreatic Islet Development
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The small GTPase Ran orchestrates pleiotropic cellular responses of nucleo-cytoplasmic shuttling, mitosis and subcellular trafficking, but whether deregulation of these pathways contributes to disease pathogenesis has remained elusive. Here, we generated transgenic mice expressing wild type (WT) Ran, loss-of-function Ran T24N mutant or constitutive...
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Full title
Essential Role of the Small GTPase Ran in Postnatal Pancreatic Islet Development
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TN_cdi_plos_journals_1310008033
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1310008033
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0027879
