Mitochondrial DNA haplogroup background affects LHON, but not suspected LHON, in Chinese patients
Mitochondrial DNA haplogroup background affects LHON, but not suspected LHON, in Chinese patients
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Recent studies have shown that mtDNA background could affect the clinical expression of Leber hereditary optic neuropathy (LHON). We analyzed the mitochondrial DNA (mtDNA) variation of 304 Chinese patients with m.11778G>A (sample #1) and of 843 suspected LHON patients who lack the three primary mutations (sample #2) to discern mtDNA haplogroup effe...
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Full title
Mitochondrial DNA haplogroup background affects LHON, but not suspected LHON, in Chinese patients
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TN_cdi_plos_journals_1312093448
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312093448
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0027750
