Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of huma...
Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes
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United States: Public Library of Science
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English
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United States: Public Library of Science
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MicroRNAs (miRs) negatively regulate transcription and are important determinants of normal heart development and heart failure pathogenesis. Despite the significant knowledge gained in mouse studies, their functional roles in human (h) heart remain elusive.
We hypothesized that miRs that figure prominently in cardiac differentiation are differe...
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Full title
Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes
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TN_cdi_plos_journals_1312157922
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312157922
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0027417
