Expression of DNMT1 and DNMT3a Are Regulated by GLI1 in Human Pancreatic Cancer
Expression of DNMT1 and DNMT3a Are Regulated by GLI1 in Human Pancreatic Cancer
About this item
Full title
Author / Creator
He, ShanShan , Wang, Feng , Yang, LiJuan , Guo, ChuanYong , Wan, Rong , Ke, AiWu , Xu, Ling , Hu, GuoYong , Xu, XuanFu , Shen, Jie and Wang, XingPeng
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
GLI1, as an indispensable transcriptional factor of Hedgehog signaling pathway, plays an important role in the development of pancreatic cancer (PC). DNA methyltransferases (DNMTs) mediate the methylation of quantity of tumor-related genes. Our study aimed to explore the relationship between GLI1 and DNMTs.
Expressions of GLI1 and DNMTs were det...
Alternative Titles
Full title
Expression of DNMT1 and DNMT3a Are Regulated by GLI1 in Human Pancreatic Cancer
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1312159207
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312159207
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0027684
