Farnesol-Induced Apoptosis in Candida albicans Is Mediated by Cdr1-p Extrusion and Depletion of Intr...
Farnesol-Induced Apoptosis in Candida albicans Is Mediated by Cdr1-p Extrusion and Depletion of Intracellular Glutathione
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Farnesol is a key derivative in the sterol biosynthesis pathway in eukaryotic cells previously identified as a quorum sensing molecule in the human fungal pathogen Candida albicans. Recently, we demonstrated that above threshold concentrations, farnesol is capable of triggering apoptosis in C. albicans. However, the exact mechanism of farnesol cyto...
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Farnesol-Induced Apoptosis in Candida albicans Is Mediated by Cdr1-p Extrusion and Depletion of Intracellular Glutathione
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TN_cdi_plos_journals_1312160464
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312160464
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0028830
