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The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of...

The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312164013

The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes

About this item

Full title

The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-12, Vol.6 (12), p.e29564-e29564

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The human pathogen Mycobacterium tuberculosis (Mtb) has the originality of possessing a multifunctional mega-enzyme FAS-I (Fatty Acid Synthase-I), together with a multi-protein FAS-II system, to carry out the biosynthesis of common and of specific long chain fatty acids: the mycolic acids (MA). MA are the main constituents of the external mycomembr...

Alternative Titles

Full title

The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312164013

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312164013

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0029564

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