LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor
LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Lysophosphatidic acid (LPA), a lipid mediator enriched in serum, stimulates cell migration, proliferation and other functions in many cell types. LPA acts on six known G protein-coupled receptors, termed LPA(1-6), showing both overlapping and distinct signaling properties. Here we show that, unexpectedly, LPA and serum almost completely inhibit the...
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Full title
LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor
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TN_cdi_plos_journals_1312178597
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312178597
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0029260
