Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons
Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The neuropathology of Parkinson's disease (PD) includes loss of dopaminergic neurons in the substantia nigra, nitrated alpha-synuclein (N-alpha-Syn) enriched intraneuronal inclusions or Lewy bodies and neuroinflammation. While the contribution of innate microglial inflammatory activities to disease are known, evidence for how adaptive immune mechan...
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Full title
Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons
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TN_cdi_plos_journals_1312181768
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312181768
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0001376
