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MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology

MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312185086

MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology

About this item

Full title

MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology

Publisher

United States: Public Library of Science

Journal title

PloS one, 2008-02, Vol.3 (2), p.e1616

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Age-related increases in monoamine oxidase B (MAO-B) may contribute to neurodegeneration associated with Parkinson's disease (PD). The MAO-B inhibitor deprenyl, a long-standing antiparkinsonian therapy, is currently used clinically in concert with the dopamine precursor L-DOPA. Clinical studies suggesting that deprenyl treatment alone is not protec...

Alternative Titles

Full title

MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312185086

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312185086

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0001616

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