Germline mutation in RNASEL predicts increased risk of head and neck, uterine cervix and breast canc...
Germline mutation in RNASEL predicts increased risk of head and neck, uterine cervix and breast cancer
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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THE BACKGROUND: Ribonuclease L (RNASEL), encoding the 2'-5'-oligoadenylate (2-5A)-dependent RNase L, is a key enzyme in the interferon induced antiviral and anti-proliferate pathway. Mutations in RNASEL segregate with the disease in prostate cancer families and specific genotypes are associated with an increased risk of prostate cancer. Infection b...
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Full title
Germline mutation in RNASEL predicts increased risk of head and neck, uterine cervix and breast cancer
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TN_cdi_plos_journals_1312289049
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312289049
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0002492
