Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis
Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Overexpression of the human c-MYC (MYC) oncogene is one of the most frequently implicated events in the pathogenesis of hepatocellular carcinoma (HCC). Previously, we have shown in a conditional transgenic mouse model that MYC overexpression is restrained from inducing mitotic cellular division and tumorigenesis in the adult liver; whereas, in mark...
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Full title
Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis
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TN_cdi_plos_journals_1312290015
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312290015
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0002493
