The Role of Cardiac Troponin T Quantity and Function in Cardiac Development and Dilated Cardiomyopat...
The Role of Cardiac Troponin T Quantity and Function in Cardiac Development and Dilated Cardiomyopathy
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Author / Creator
Ahmad, Ferhaan , Banerjee, Sanjay K. , Lage, Michele L. , Huang, Xueyin N. , Smith, Stephen H. , Saba, Samir , Rager, Jennifer , Conner, David A. , Janczewski, Andrzej M. , Tobita, Kimimasa , Tinney, Joseph P. , Moskowitz, Ivan P. , Perez-Atayde, Antonio R. , Keller, Bradley B. , Mathier, Michael A. , Shroff, Sanjeev G. , Seidman, Christine E. and Seidman, J. G.
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Hypertrophic (HCM) and dilated (DCM) cardiomyopathies result from sarcomeric protein mutations, including cardiac troponin T (cTnT, TNNT2). We determined whether TNNT2 mutations cause cardiomyopathies by altering cTnT function or quantity; whether the severity of DCM is related to the ratio of mutant to wildtype cTnT; whether Ca(2+) desensitization...
Alternative Titles
Full title
The Role of Cardiac Troponin T Quantity and Function in Cardiac Development and Dilated Cardiomyopathy
Authors, Artists and Contributors
Author / Creator
Banerjee, Sanjay K.
Lage, Michele L.
Huang, Xueyin N.
Smith, Stephen H.
Saba, Samir
Rager, Jennifer
Conner, David A.
Janczewski, Andrzej M.
Tobita, Kimimasa
Tinney, Joseph P.
Moskowitz, Ivan P.
Perez-Atayde, Antonio R.
Keller, Bradley B.
Mathier, Michael A.
Shroff, Sanjeev G.
Seidman, Christine E.
Seidman, J. G.
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1312305883
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312305883
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0002642
