Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease
Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease
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Author / Creator
Chen, Zhi-Hua , Kim, Hong Pyo , Sciurba, Frank C. , Lee, Seon-Jin , Feghali-Bostwick, Carol , Stolz, Donna B. , Dhir, Rajiv , Landreneau, Rodney J. , Schuchert, Mathew J. , Yousem, Samuel A. , Nakahira, Kiichi , Pilewski, Joseph M. , Lee, Janet S. , Zhang, Yingze , Ryter, Stefan W. and Choi, Augustine M. K.
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by abnormal cellular responses to cigarette smoke, resulting in tissue destruction and airflow limitation. Autophagy is a degradative process involving lysosomal turnover of cellular components, though its role in human diseases remains unclear.
Increased au...
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Full title
Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease
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TN_cdi_plos_journals_1312307372
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312307372
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0003316