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The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy

The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312310673

The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy

About this item

Full title

The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy

Publisher

United States: Public Library of Science

Journal title

PloS one, 2008-07, Vol.3 (7), p.e2675-e2675

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In proliferative diabetic retinopathy (PDR), vascular endothelial growth factor (VEGF) and connective tissue growth factor (CTGF) cause blindness by neovascularization and subsequent fibrosis, but their relative contribution to both processes is unknown. We hypothesize that the balance between levels of pro-angiogenic VEGF and pro-fibrotic CTGF reg...

Alternative Titles

Full title

The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312310673

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312310673

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0002675

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