Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion
Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Although the most common mechanism underlying congenital hyperinsulinism is dysfunction of the pancreatic ATP-sensitive potassium channel, the pathogenesis and genetic origins of this disease remains largely unexplained in more than half of all patients. UCP2 knockout mice exhibit an hyperinsulinemic hypoglycemia, suggesting an involvement of UCP2...
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Full title
Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion
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TN_cdi_plos_journals_1312320125
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312320125
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0003850
