JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells
JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Cytokines contribute to pancreatic beta-cell apoptosis in type 1 diabetes (T1D) by modulation of beta-cell gene expression networks. The transcription factor Activator Protein-1 (AP-1) is a key regulator of inflammation and apoptosis. We presently evaluated the function of the AP-1 subunit JunB in cytokine-mediated beta-cell dysfunction and death....
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Full title
JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells
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TN_cdi_plos_journals_1312438698
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312438698
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0003030
