PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence
PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Inactivation of the transcriptional regulator PhoP results in Mycobacterium tuberculosis attenuation. Preclinical testing has shown that attenuated M. tuberculosis phoP mutants hold promise as safe and effective live vaccine candidates. We focused this study to decipher the virulence networks regulated by PhoP. A combined transcriptomic and proteom...
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Full title
PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence
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TN_cdi_plos_journals_1312439468
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312439468
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0003496