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PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence

PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312439468

PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence

About this item

Full title

PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence

Publisher

United States: Public Library of Science

Journal title

PloS one, 2008-10, Vol.3 (10), p.e3496-e3496

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Inactivation of the transcriptional regulator PhoP results in Mycobacterium tuberculosis attenuation. Preclinical testing has shown that attenuated M. tuberculosis phoP mutants hold promise as safe and effective live vaccine candidates. We focused this study to decipher the virulence networks regulated by PhoP. A combined transcriptomic and proteom...

Alternative Titles

Full title

PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1312439468

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1312439468

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0003496

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