A Kinetic Model of Dopamine- and Calcium-Dependent Striatal Synaptic Plasticity
A Kinetic Model of Dopamine- and Calcium-Dependent Striatal Synaptic Plasticity
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Corticostriatal synapse plasticity of medium spiny neurons is regulated by glutamate input from the cortex and dopamine input from the substantia nigra. While cortical stimulation alone results in long-term depression (LTD), the combination with dopamine switches LTD to long-term potentiation (LTP), which is known as dopamine-dependent plasticity....
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Full title
A Kinetic Model of Dopamine- and Calcium-Dependent Striatal Synaptic Plasticity
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TN_cdi_plos_journals_1313173042
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313173042
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1000670
