Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesion
Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesion
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The LFA-1 integrin plays a pivotal role in sustained leukocyte adhesion to the endothelial surface, which is a precondition for leukocyte recruitment into inflammation sites. Strong correlative evidence implicates LFA-1 clustering as being essential for sustained adhesion, and it may also facilitate rebinding events with its ligand ICAM-1. We canno...
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Full title
Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesion
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TN_cdi_plos_journals_1313173108
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313173108
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1000681