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Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesion

Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313173108

Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesion

About this item

Full title

Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesion

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2010-02, Vol.6 (2), p.e1000681-e1000681

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The LFA-1 integrin plays a pivotal role in sustained leukocyte adhesion to the endothelial surface, which is a precondition for leukocyte recruitment into inflammation sites. Strong correlative evidence implicates LFA-1 clustering as being essential for sustained adhesion, and it may also facilitate rebinding events with its ligand ICAM-1. We canno...

Alternative Titles

Full title

Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesion

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1313173108

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313173108

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1000681

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