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Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics

Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313184938

Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics

About this item

Full title

Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2011-02, Vol.7 (2), p.e1001081-e1001081

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Relatively little is known about the viral factors contributing to the lethality of the 1918 pandemic, although its unparalleled virulence was likely due in part to the newly discovered PB1-F2 protein. This protein, while unnecessary for replication, increases apoptosis in monocytes, alters viral polymerase activity in vitro, enhances inflammation...

Alternative Titles

Full title

Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1313184938

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313184938

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1001081

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