The CanOE Strategy: Integrating Genomic and Metabolic Contexts across Multiple Prokaryote Genomes to...
The CanOE Strategy: Integrating Genomic and Metabolic Contexts across Multiple Prokaryote Genomes to Find Candidate Genes for Orphan Enzymes
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Of all biochemically characterized metabolic reactions formalized by the IUBMB, over one out of four have yet to be associated with a nucleic or protein sequence, i.e. are sequence-orphan enzymatic activities. Few bioinformatics annotation tools are able to propose candidate genes for such activities by exploiting context-dependent rather than sequ...
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The CanOE Strategy: Integrating Genomic and Metabolic Contexts across Multiple Prokaryote Genomes to Find Candidate Genes for Orphan Enzymes
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TN_cdi_plos_journals_1313185550
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313185550
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1002540
