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Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bon...

Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bon...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313504236

Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength

About this item

Full title

Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2012-08, Vol.8 (8), p.e1002858

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Osteoporosis is a common polygenic disease and global healthcare priority but its genetic basis remains largely unknown. We report a high-throughput multi-parameter phenotype screen to identify functionally significant skeletal phenotypes in mice generated by the Wellcome Trust Sanger Institute Mouse Genetics Project and discover novel genes that m...

Alternative Titles

Full title

Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1313504236

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313504236

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1002858

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