Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes i...
Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population
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Full title
Author / Creator
Bell, Jordana T. , Tsai, Pei-Chien , Yang, Tsun-Po , Pidsley, Ruth , Nisbet, James , Glass, Daniel , Mangino, Massimo , Zhai, Guangju , Zhang, Feng , Valdes, Ana , Shin, So-Youn , Dempster, Emma L. , Murray, Robin M. , Grundberg, Elin , Hedman, Asa K. , Nica, Alexandra , Small, Kerrin S. , Dermitzakis, Emmanouil T. , McCarthy, Mark I. , Mill, Jonathan , Spector, Tim D. , Deloukas, Panos , The MuTHER Consortium and MuTHER Consortium
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Age-related changes in DNA methylation have been implicated in cellular senescence and longevity, yet the causes and functional consequences of these variants remain unclear. To elucidate the role of age-related epigenetic changes in healthy ageing and potential longevity, we tested for association between whole-blood DNA methylation patterns in 17...
Alternative Titles
Full title
Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population
Authors, Artists and Contributors
Author / Creator
Tsai, Pei-Chien
Yang, Tsun-Po
Pidsley, Ruth
Nisbet, James
Glass, Daniel
Mangino, Massimo
Zhai, Guangju
Zhang, Feng
Valdes, Ana
Shin, So-Youn
Dempster, Emma L.
Murray, Robin M.
Grundberg, Elin
Hedman, Asa K.
Nica, Alexandra
Small, Kerrin S.
Dermitzakis, Emmanouil T.
McCarthy, Mark I.
Mill, Jonathan
Spector, Tim D.
Deloukas, Panos
The MuTHER Consortium
MuTHER Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1313504782
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313504782
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002629
