Positive Epistasis Drives the Acquisition of Multidrug Resistance
Positive Epistasis Drives the Acquisition of Multidrug Resistance
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The evolution of multiple antibiotic resistance is an increasing global problem. Resistance mutations are known to impair fitness, and the evolution of resistance to multiple drugs depends both on their costs individually and on how they interact--epistasis. Information on the level of epistasis between antibiotic resistance mutations is of key imp...
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Full title
Positive Epistasis Drives the Acquisition of Multidrug Resistance
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TN_cdi_plos_journals_1313523177
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313523177
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000578
