Interactions between Cells with Distinct Mutations in c-MYC and Pten in Prostate Cancer
Interactions between Cells with Distinct Mutations in c-MYC and Pten in Prostate Cancer
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United States: Public Library of Science
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English
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United States: Public Library of Science
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In human somatic tumorigenesis, mutations are thought to arise sporadically in individual cells surrounded by unaffected cells. This contrasts with most current transgenic models where mutations are induced synchronously in entire cell populations. Here we have modeled sporadic oncogene activation using a transgenic mouse in which c-MYC is focally...
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Interactions between Cells with Distinct Mutations in c-MYC and Pten in Prostate Cancer
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TN_cdi_plos_journals_1313530350
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313530350
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000542