Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Applicatio...
Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits
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Full title
Author / Creator
Paul, Dirk S. , Nisbet, James P. , Yang, Tsun-Po , Meacham, Stuart , Rendon, Augusto , Hautaviita, Katta , Tallila, Jonna , White, Jacqui , Tijssen, Marloes R. , Sivapalaratnam, Suthesh , Basart, Hanneke , Trip, Mieke D. , Göttgens, Berthold , Soranzo, Nicole , Ouwehand, Willem H. , Deloukas, Panos , Consortium Cardiogenics , Consortium MuTHER , Cardiogenics Consortium and MuTHER Consortium
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Turning genetic discoveries identified in genome-wide association (GWA) studies into biological mechanisms is an important challenge in human genetics. Many GWA signals map outside exons, suggesting that the associated variants may lie within regulatory regions. We applied the formaldehyde-assisted isolation of regulatory elements (FAIRE) method in...
Alternative Titles
Full title
Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits
Authors, Artists and Contributors
Author / Creator
Nisbet, James P.
Yang, Tsun-Po
Meacham, Stuart
Rendon, Augusto
Hautaviita, Katta
Tallila, Jonna
White, Jacqui
Tijssen, Marloes R.
Sivapalaratnam, Suthesh
Basart, Hanneke
Trip, Mieke D.
Göttgens, Berthold
Soranzo, Nicole
Ouwehand, Willem H.
Deloukas, Panos
Consortium Cardiogenics
Consortium MuTHER
Cardiogenics Consortium
MuTHER Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1313537003
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313537003
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002139
