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The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of ger...

The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of ger...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313538198

The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs

About this item

Full title

The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2012-04, Vol.8 (4), p.e1002617-e1002617

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Small RNAs regulate diverse biological processes by directing effector proteins called Argonautes to silence complementary mRNAs. Maturation of some classes of small RNAs involves terminal 2'-O-methylation to prevent degradation. This modification is catalyzed by members of the conserved HEN1 RNA methyltransferase family. In animals, Piwi-interacti...

Alternative Titles

Full title

The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1313538198

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313538198

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1002617

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