Evolution of minimal specificity and promiscuity in steroid hormone receptors
Evolution of minimal specificity and promiscuity in steroid hormone receptors
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Most proteins are regulated by physical interactions with other molecules; some are highly specific, but others interact with many partners. Despite much speculation, we know little about how and why specificity/promiscuity evolves in natural proteins. It is widely assumed that specific proteins evolved from more promiscuous ancient forms and that...
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Full title
Evolution of minimal specificity and promiscuity in steroid hormone receptors
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TN_cdi_plos_journals_1313540912
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313540912
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1003072
