Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence u...
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations
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ENGAGE Consortium , KORA Study , EUROSPAN Consortium , PROCARDIS Consortium , WTCCC , for the EUROSPAN Consortium , for the PROCARDIS Consortium , for the ENGAGE Consortium , for the KORA Study , for the WTCCC , Kolz, Melanie , Johnson, Toby , Sanna, Serena , Teumer, Alexander , Vitart, Veronique , Perola, Markus , Mangino, Massimo , Albrecht, Eva , Wallace, Chris , Farrall, Martin , Johansson, Asa , Nyholt, Dale R , Aulchenko, Yurii , Beckmann, Jacques S , Bergmann, Sven , Bochud, Murielle , Brown, Morris , Campbell, Harry , Connell, John , Dominiczak, Anna , Homuth, Georg , Lamina, Claudia , McCarthy, Mark I , Meitinger, Thomas , Mooser, Vincent , Munroe, Patricia , Nauck, Matthias , Peden, John , Prokisch, Holger , Salo, Perttu , Salomaa, Veikko , Samani, Nilesh J , Schlessinger, David , Uda, Manuela , Völker, Uwe , Waeber, Gérard , Waterworth, Dawn , Wang-Sattler, Rui , Wright, Alan F , Adamski, Jerzy , Whitfield, John B , Gyllensten, Ulf , Wilson, James F , Rudan, Igor , Pramstaller, Peter , Watkins, Hugh , Doering, Angela , Wichmann, H-Erich , Spector, Tim D , Peltonen, Leena , Völzke, Henry , Nagaraja, Ramaiah , Vollenweider, Peter , Caulfield, Mark , Illig, Thomas and Gieger, Christian
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Elevated serum uric acid levels cause gout and are a risk factor for cardiovascular disease and diabetes. To investigate the polygenetic basis of serum uric acid levels, we conducted a meta-analysis of genome-wide association scans from 14 studies totalling 28,141 participants of European descent, resulting in identification of 954 SNPs distributed...
Alternative Titles
Full title
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations
Authors, Artists and Contributors
Author / Creator
KORA Study
EUROSPAN Consortium
PROCARDIS Consortium
WTCCC
for the EUROSPAN Consortium
for the PROCARDIS Consortium
for the ENGAGE Consortium
for the KORA Study
for the WTCCC
Kolz, Melanie
Johnson, Toby
Sanna, Serena
Teumer, Alexander
Vitart, Veronique
Perola, Markus
Mangino, Massimo
Albrecht, Eva
Wallace, Chris
Farrall, Martin
Johansson, Asa
Nyholt, Dale R
Aulchenko, Yurii
Beckmann, Jacques S
Bergmann, Sven
Bochud, Murielle
Brown, Morris
Campbell, Harry
Connell, John
Dominiczak, Anna
Homuth, Georg
Lamina, Claudia
McCarthy, Mark I
Meitinger, Thomas
Mooser, Vincent
Munroe, Patricia
Nauck, Matthias
Peden, John
Prokisch, Holger
Salo, Perttu
Salomaa, Veikko
Samani, Nilesh J
Schlessinger, David
Uda, Manuela
Völker, Uwe
Waeber, Gérard
Waterworth, Dawn
Wang-Sattler, Rui
Wright, Alan F
Adamski, Jerzy
Whitfield, John B
Gyllensten, Ulf
Wilson, James F
Rudan, Igor
Pramstaller, Peter
Watkins, Hugh
Doering, Angela
Wichmann, H-Erich
Spector, Tim D
Peltonen, Leena
Völzke, Henry
Nagaraja, Ramaiah
Vollenweider, Peter
Caulfield, Mark
Illig, Thomas
Gieger, Christian
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1313541202
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313541202
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000504
