A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Decades of study have revealed more than 100 ribonucleoside structures incorporated as post-transcriptional modifications mainly in tRNA and rRNA, yet the larger functional dynamics of this conserved system are unclear. To this end, we developed a highly precise mass spectrometric method to quantify tRNA modifications in Saccharomyces cerevisiae. O...
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Full title
A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
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TN_cdi_plos_journals_1313544920
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313544920
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1001247
