Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
About this item
Full title
Author / Creator
Schumacher, Björn , van der Pluijm, Ingrid , Moorhouse, Michael J. , Kosteas, Theodore , Robinson, Andria Rasile , Suh, Yousin , Breit, Timo M. , van Steeg, Harry , Niedernhofer, Laura J. , van IJcken, Wilfred , Bartke, Andrzej , Spindler, Stephen R. , Hoeijmakers, Jan H. J. , van der Horst, Gijsbertus T. J. and Garinis, George A.
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Mutant dwarf and calorie-restricted mice benefit from healthy aging and unusually long lifespan. In contrast, mouse models for DNA repair-deficient progeroid syndromes age and die prematurely. To identify mechanisms that regulate mammalian longevity, we quantified the parallels between the genome-wide liver expression profiles of mice with those tw...
Alternative Titles
Full title
Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
Authors, Artists and Contributors
Author / Creator
van der Pluijm, Ingrid
Moorhouse, Michael J.
Kosteas, Theodore
Robinson, Andria Rasile
Suh, Yousin
Breit, Timo M.
van Steeg, Harry
Niedernhofer, Laura J.
van IJcken, Wilfred
Bartke, Andrzej
Spindler, Stephen R.
Hoeijmakers, Jan H. J.
van der Horst, Gijsbertus T. J.
Garinis, George A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1313549636
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313549636
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000161
