Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor
Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor
About this item
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Author / Creator
Keller, Matthew C. , Simonson, Matthew A. , Ripke, Stephan , Neale, Ben M. , Gejman, Pablo V. , Howrigan, Daniel P. , Lee, Sang Hong , Lencz, Todd , Levinson, Douglas F. , Sullivan, Patrick F. , The Schizophrenia Psychiatric Genome-Wide Association Study Consortium and Schizophrenia Psychiatric Genome-Wide Association Study Consortium
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Autozygosity occurs when two chromosomal segments that are identical from a common ancestor are inherited from each parent. This occurs at high rates in the offspring of mates who are closely related (inbreeding), but also occurs at lower levels among the offspring of distantly related mates. Here, we use runs of homozygosity in genome-wide SNP dat...
Alternative Titles
Full title
Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor
Authors, Artists and Contributors
Author / Creator
Simonson, Matthew A.
Ripke, Stephan
Neale, Ben M.
Gejman, Pablo V.
Howrigan, Daniel P.
Lee, Sang Hong
Lencz, Todd
Levinson, Douglas F.
Sullivan, Patrick F.
The Schizophrenia Psychiatric Genome-Wide Association Study Consortium
Schizophrenia Psychiatric Genome-Wide Association Study Consortium
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1313574822
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313574822
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002656
