Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice
Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Maintenance of normal mineral ion homeostasis is crucial for many biological activities, including proper mineralization of the skeleton. Parathyroid hormone (PTH), Klotho, and FGF23 have been shown to act as key regulators of serum calcium and phosphate homeostasis through a complex feedback mechanism. The phenotypes of Fgf23(-/-) and Klotho(-/-)...
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Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice
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TN_cdi_plos_journals_1313611867
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1313611867
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1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1002726
