Antifungal chemical compounds identified using a C. elegans pathogenicity assay
Antifungal chemical compounds identified using a C. elegans pathogenicity assay
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
There is an urgent need for the development of new antifungal agents. A facile in vivo model that evaluates libraries of chemical compounds could solve some of the main obstacles in current antifungal discovery. We show that Candida albicans, as well as other Candida species, are ingested by Caenorhabditis elegans and establish a persistent lethal...
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Full title
Antifungal chemical compounds identified using a C. elegans pathogenicity assay
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TN_cdi_plos_journals_1314350182
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1314350182
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.0030018
