Mouse genome-wide association mapping needs linkage analysis to avoid false-positive Loci
Mouse genome-wide association mapping needs linkage analysis to avoid false-positive Loci
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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We carried out genome-wide association (GWA) studies in inbred mouse strains characterized for their lung tumor susceptibility phenotypes (spontaneous or urethane-induced) with panels of 12,959 (13K) or 138,793 (140K) single-nucleotide polymorphisms (SNPs). Above the statistical thresholds, we detected only SNP rs3681853 on Chromosome 5, two SNPs i...
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Full title
Mouse genome-wide association mapping needs linkage analysis to avoid false-positive Loci
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TN_cdi_plos_journals_1314378483
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1314378483
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1000331
