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Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity

Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1318938748

Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity

About this item

Full title

Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-12, Vol.5 (12), p.e15343-e15343

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

West Nile virus (WNV) infection can result in severe neuroinvasive disease, particularly in persons with advanced age. As rodent models demonstrate that T cells play an important role in limiting WNV infection, and strong T cell responses to WNV have been observed in humans, we postulated that inadequate antiviral T cell immunity was involved in ne...

Alternative Titles

Full title

Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1318938748

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1318938748

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0015343

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