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O-Glycosylation Regulates Ubiquitination and Degradation of the Anti-Inflammatory Protein A20 to Acc...

O-Glycosylation Regulates Ubiquitination and Degradation of the Anti-Inflammatory Protein A20 to Acc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1318939755

O-Glycosylation Regulates Ubiquitination and Degradation of the Anti-Inflammatory Protein A20 to Accelerate Atherosclerosis in Diabetic ApoE-Null Mice

About this item

Full title

O-Glycosylation Regulates Ubiquitination and Degradation of the Anti-Inflammatory Protein A20 to Accelerate Atherosclerosis in Diabetic ApoE-Null Mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-12, Vol.5 (12), p.e14240-e14240

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Accelerated atherosclerosis is the leading cause of morbidity and mortality in diabetic patients. Hyperglycemia is a recognized independent risk factor for heightened atherogenesis in diabetes mellitus (DM). However, our understanding of the mechanisms underlying glucose damage to the vasculature remains incomplete.
High glucose and hyperglycemi...

Alternative Titles

Full title

O-Glycosylation Regulates Ubiquitination and Degradation of the Anti-Inflammatory Protein A20 to Accelerate Atherosclerosis in Diabetic ApoE-Null Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1318939755

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1318939755

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0014240

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