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Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atheroscleros...

Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atheroscleros...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1322080011

Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation

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Full title

Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012, Vol.7 (1), p.e29371-e29371

Language

English

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Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

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Scope and Contents

Contents

We have recently identified conventional B2 cells as atherogenic and B1a cells as atheroprotective in hypercholesterolemic ApoE(-/-) mice. Here, we examined the development of atherosclerosis in BAFF-R deficient ApoE(-/-) mice because B2 cells but not B1a cells are selectively depleted in BAFF-R deficient mice. We fed BAFF-R(-/-) ApoE(-/-) (BaffR.A...

Alternative Titles

Full title

Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation

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Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1322080011

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1322080011

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0029371

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