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Poke weed mitogen requires Toll-like receptor ligands for proliferative activity in human and murine...

Poke weed mitogen requires Toll-like receptor ligands for proliferative activity in human and murine...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1322351819

Poke weed mitogen requires Toll-like receptor ligands for proliferative activity in human and murine B lymphocytes

About this item

Full title

Poke weed mitogen requires Toll-like receptor ligands for proliferative activity in human and murine B lymphocytes

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-01, Vol.7 (1), p.e29806

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Poke weed mitogen (PWM), a lectin purified from Phytolacca americana is frequently used as a B cell-specific stimulus to trigger proliferation and immunoglobulin secretion. In the present study we investigated the mechanisms underlying the B cell stimulatory capacity of PWM. Strikingly, we observed that highly purified PWM preparations failed to in...

Alternative Titles

Full title

Poke weed mitogen requires Toll-like receptor ligands for proliferative activity in human and murine B lymphocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1322351819

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1322351819

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0029806

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