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A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C

A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323071467

A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C

About this item

Full title

A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-01, Vol.7 (1), p.e30376

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Caspase-6 is a cysteinyl protease implicated in neurodegenerative conditions including Alzheimer's and Huntington's disease making it an attractive target for therapeutic intervention. A greater understanding of the role of caspase-6 in disease has been hampered by a lack of suitable cellular assays capable of specifically detecting caspase-6 activ...

Alternative Titles

Full title

A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1323071467

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323071467

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0030376

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