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Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regio...

Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323077693

Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions

About this item

Full title

Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-01, Vol.7 (1), p.e30036-e30036

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The APOBEC3 gene cluster encodes six cytidine deaminases (A3A-C, A3DE, A3F-H) with single stranded DNA (ssDNA) substrate specificity. For the moment A3A is the only enzyme that can initiate catabolism of both mitochondrial and nuclear DNA. Human A3A expression is initiated from two different methionine codons M1 or M13, both of which are in adequat...

Alternative Titles

Full title

Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1323077693

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323077693

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0030036

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