A novel Atoh1 "self-terminating" mouse model reveals the necessity of proper Atoh1 level and duratio...
A novel Atoh1 "self-terminating" mouse model reveals the necessity of proper Atoh1 level and duration for hair cell differentiation and viability
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Atonal homolog1 (Atoh1) is a bHLH transcription factor essential for inner ear hair cell differentiation. Targeted expression of Atoh1 at various stages in development can result in hair cell differentiation in the ear. However, the level and duration of Atoh1 expression required for proper hair cell differentiation and maintenance remain unknown....
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A novel Atoh1 "self-terminating" mouse model reveals the necessity of proper Atoh1 level and duration for hair cell differentiation and viability
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TN_cdi_plos_journals_1323091144
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323091144
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0030358
