The Chemotactic Defect in Wiskott-Aldrich Syndrome Macrophages Is Due to the Reduced Persistence of...
The Chemotactic Defect in Wiskott-Aldrich Syndrome Macrophages Is Due to the Reduced Persistence of Directional Protrusions
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Wiskott-Aldrich syndrome protein (WASp) is an actin nucleation promoting factor that is required for macrophages to directionally migrate towards various chemoattractants. The chemotaxis defect of WASp-deficient cells and its activation by Cdc42 in vivo suggest that WASp plays a role in directional sensing, however, its precise role in macrophage c...
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Full title
The Chemotactic Defect in Wiskott-Aldrich Syndrome Macrophages Is Due to the Reduced Persistence of Directional Protrusions
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TN_cdi_plos_journals_1323091662
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323091662
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0030033
