TGFBR1 Intralocus Epistatic Interaction as a Risk Factor for Colorectal Cancer
TGFBR1 Intralocus Epistatic Interaction as a Risk Factor for Colorectal Cancer
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Author / Creator
Martinez-Canto, Ana , Castillejo, Adela , Mata-Balaguer, Trinidad , Castillejo, Maria-Isabel , Hernandez-Illan, Eva , Irles, Esperanza , Barbera, Victor Manuel , Egoavil, Cecilia , Guarinos, Carla , Alenda, Cristina , Ochoa, Enrique , Lazaro, Rafael , Fajardo, Silvia , Lacueva, Javier , Calpena, Rafael and Soto, Jose Luis
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
In colorectal cancer (CRC), an inherited susceptibility risk affects about 35% of patients, whereas high-penetrance germline mutations account for <6% of cases. A considerable proportion of sporadic tumors could be explained by the coinheritance of multiple low-penetrance variants, some of which are common. We assessed the susceptibility to CRC con...
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Full title
TGFBR1 Intralocus Epistatic Interaction as a Risk Factor for Colorectal Cancer
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TN_cdi_plos_journals_1323411880
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323411880
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0030812
