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Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival

Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323440276

Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival

About this item

Full title

Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-01, Vol.7 (1), p.e30853-e30853

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In the mammalian inner ear neurosensory cell fate depends on three closely related transcription factors, Atoh1 for hair cells and Neurog1 and Neurod1 for neurons. We have previously shown that neuronal cell fate can be altered towards hair cell fate by eliminating Neurod1 mediated repression of Atoh1 expression in neurons. To test whether a simila...

Alternative Titles

Full title

Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1323440276

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323440276

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0030853

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