Role of AMP-activated protein kinase on steroid hormone biosynthesis in adrenal NCI-H295R cells
Role of AMP-activated protein kinase on steroid hormone biosynthesis in adrenal NCI-H295R cells
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Regulation of human androgen biosynthesis is poorly understood. However, detailed knowledge is needed to eventually solve disorders with androgen dysbalance. We showed that starvation growth conditions shift steroidogenesis of human adrenal NCI-H295R cells towards androgen production attributable to decreased HSD3B2 expression and activity and incr...
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Full title
Role of AMP-activated protein kinase on steroid hormone biosynthesis in adrenal NCI-H295R cells
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TN_cdi_plos_journals_1323441023
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1323441023
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0030956
